Chuang, Huai-Hu A.
Assistant Professor
research
research and scholarship focus
- Understanding the molecular basis of electric signal modulations in primary sensory neurons and their biomedical relevance
- Examine logical designs of electrical signaling network in excitable cells. We use a variety of methods to examine the issue, including molecular biology, physiology, pharmacology, and biophysics.
background
educational background
- M.D., School of Medicine at National Taiwan University
- Ph.D., University of California
publications
selected publications (listing in progress)
- Chuang H, Neuhausser WM, Julius D. The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature sensitive TRP channel. (2004) Neuron, 43: 859-869.
- Jordt SE, Bautista DM, Chuang H, McKemy DD, Zygmunt PM, Hogestatt ED, Meng ID, Julius D. Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. (2004) Nature, 427: 260-5.
- Chuang H, Prescott ED, Kong H, Shields S, Jordt SE, Basbaum AI, Chao MV, and Julius D. (2001) Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition. (2001) Nature, 411: 957-962.
- Whistler JL, Chuang H, Chu P, Jan LY, von Zastrow M, (1999). Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction. Neuron, 23(4): 737-746.
- Zygmunt PM, Petersson J, Andersson DA, Chuang H, Sorgard M, Di Marzo V, Julius D, and Hogestatt ED. (1999). Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide. Nature, 400: 452-457.
