Hormonal regulation of the differentiation and function of ovarian follicles

Differentiation and relative roles of the two endocrine cell types in the follicle

Theca and granulosa cells

Relative roles of the two pituitary gonadotropins, LH and FSH, in the regulation of follicular steroid production

Isolating and culturing theca and granulosa cells from follicles at defined stages of follicular development

Mechanisms by which a few follicles are selected to complete development and ovulate

Monitor the growth and regression of follicles over time in vivo with ultrasonography

Cattle, horses, and rats as experimental models in these studies