Boisclair, Yves R

Professor

My professional activities are centered around an understanding of the role of hormones in regulating mammalian metabolism. My research activities involve many animal models (mouse, sheep and cattle), based on the fact that each offers unique opportunities and unique metabolic challenges. My research has implications for both animal agriculture and human health.

research

research and scholarship focus

My research focus is the regulation of metabolism by hormones. We are presently working on two hormonal systems, namely the growth-hormone--insulin-like growth factor system and the leptin system. We use a range of current molecular, cellular and organismal approaches (DNA array, transgenic technology, in vivo tracing of metabolic fluxes, etc) in mice, sheep and cattle.

primary investigator of

DEVELOPMENT AND USE OF LEPTIN RECEPTOR ANTAGONISTS TO INCREASE APPETITE AND ADAPTIVE METABOLISM IN RUMINANTS | Research Grant
REGULATION OF ALS AND ITS ROLE IN THE IGF SYSTEM. | Research Grant
ROLE OF CENTRAL LEPTIN AND MELANOCORTINS IN REGULATING INSULIN-MEDIATED GLUCOSE METABOLISM IN PERIPHERAL TISSUES OF UNDERFED RUMINANTS | Research Grant

co investigator of

EPIGENETIC REGULATION OF THE NEONATAL TH2 BIAS | Research Grant
REGULATION OF MILK FAT SYNTHESIS BY BIOACTIVE FATTY ACIDS PRODUCED DURING RUMEN BIOHYDROGENATION OF DIETARY POLYUNSATURATED FATTY ACIDS | Research Grant

research areas

animal science | collaborative research area (CALS)
biochemistry | collaborative research area (CALS)
biotechnology | collaborative research area (CALS)
dairy science | collaborative research area (CALS)
genomics | collaborative research area (CALS)
molecular biology | collaborative research area (CALS)
nutritional sciences | collaborative research area (CALS)

submitted impact statement

Regulation of the acid-labile subunit and its role in the insulin-like growth factor system | 2005 Impact statement
Role of leptin in regulating metabolism in highly productive ruminants | 2004 Impact statement
Regulation of the acid-labile subunit and its role in the insulin-like growth factor system | 2004 Impact statement

affiliations

faculty appointment in

Animal Science (AN SC) | Cornell department

member of graduate field

Animal Science | graduate field
Nutrition | graduate field

other Cornell affiliations

Mammalian Genomics | NLSI/Genomics focus area

teaching

teaching focus

I teach Biology of Lactation ( AnSc 341). This is a capstone course in physiology directed to both students interested in biomedical, and those interested in applied careers. I also teach Seminar in Animal Metabolism (AnSc 622). This class covers the latest discoveries in metabolism and seeks to broaden the scientific currency of graduate students engaged in nutritional and metabolic research.

teaches

ANSC 4960 - Internship in Animal Science (TBA -) | fall 2009 class
ANSC 4970 - Individual Study in Animal Science (TBA -) | fall 2009 class
ANSC 4980 - Undergraduate Teaching (TBA -) | fall 2009 class
ANSC 4990 - Undergraduate Research (TBA -) | fall 2009 class
ANSC 6220 - Seminar in Animal Metabolism (R 04:00:PM-05:00:PM) | fall 2009 class
ANSC 7900 - Graduate-Level Thesis Research (TBA -) | fall 2009 class
ANSC 8900 - Master's-Level Thesis Research (TBA -) | fall 2009 class
ANSC 9900 - Doctoral-Level Thesis Research (TBA -) | fall 2009 class
ANSC 3410 - Biology of Lactation (TR 09:05:AM-09:55:AM) | spring 2009 class
ANSC 3920 - Mechanisms of Animal Growth and Development (TR 12:20:PM-01:10:PM) | spring 2009 class
ANSC 4970 - Individual Study in Animal Science (TBA -) | spring 2009 class
ANSC 4980 - Undergraduate Teaching (TBA -) | spring 2009 class
ANSC 4990 - Undergraduate Research (TBA -) | spring 2009 class
ANSC 6220 - Seminar in Animal Metabolism (R 04:00:PM-05:00:PM) | spring 2009 class
ANSC 7900 - Graduate-Level Thesis Research (TBA -) | spring 2009 class
ANSC 8900 - Master's-Level Thesis Research (TBA -) | spring 2009 class
ANSC 9900 - Doctoral-Level Thesis Research (TBA -) | spring 2009 class
ANSC 6220 - Seminar in Animal Metabolism (R 04:00:PM-05:00:PM) | fall 2008 class

publications

linked articles

Keywords: cattle, growth, growth hormone, hormone, hormones, insulin-like growth factor, lactation, leptin, metabolism, molecular animal science, molecular endocrinology, mouse, sheep