Gavalchin, Jerrie

Associate Professor
Professor Gavalchin received a B.S. in Microbiology from Rutgers College, Rutgers University, New Brunswick, NJ, in 1977 and a PhD in Microbiology from The Graduate School, Rutgers University, NJ in 1983. She completed postdoctoral studies from 1982-1986 in the laboratory of Syamal Datta, Tufts University School of Medicine, Boston, MA, focusing on immumopathogenesis of SLE. In 1986, she joined the Rheumatology Section, Depts. of Medicine & Microbiology, SUNY Health Science Center, Syracuse, NY, as a Research Assistant Professor. In 1987, she was named Assistant Professor, Hematology/Oncology Section, Depts. of Medicine & Microbiology, SUNY Health Science Center, Syracuse, NY, and was promoted with tenure to Associate Professor in 1992. In 2000, she was promoted to Professor. Since 1999, she has held a joint appointment at Cornell University. From 1999-2003, she held the appointment of Adjunct Associate Professor, The Baker Institute for Animal Health, Department of Microbiology, Cornell University, Ithaca, NY. From 2003 to the present she has been Associate Professor, Department of Animal Science, Cornell University, Ithaca, NY

research

research and scholarship focus

The research being conducted in my laboratory aims to identify the pathogenetic mechanisms involved in systemic autoimmune diseases using a mouse model that develops a spontaneous lupus nephritis that is very similar to human SLE. We are also investigating whether estrogen receptor expression on immune cells is responsible, in part, for gender bias in immune responses, including autoimmune disease. Exposure to some toxic chemicals that behave like estrogen, such as dioxin, has been suggested to induce and/or modulate autoimmune diseases including SLE and diabetes, and we are determining whether these exposures are triggers or modulators of SLE. ||Other research projects that I will be involved in will include of studies of M. paratuberculosis infection in cattle and sheep, and characterization of immunosuppression in dairy cattle, with a focus to derive strategies to improve animal health, and production. One new focus is the development of a low-cost, simple, and sensitive penside diagnostic assay for Johne’s Disease. Similar approaches can be used for the development of assays against other pathogens.

research areas

affiliations

faculty appointment in

member of graduate field

teaching

teaching focus

I participate in courses where my specific area of interest and expertise is taught. At an undergraduate level, these include AN SCI 160 and AN ACI 380. I also teach AN ACI 105 with Dale Bauman. In Spring 2008, I will offer AN SCI 370, Immunology in Production Medicine. At the post-graduate level, I teach in Block IV, Host/Parasite Defenses (Cornell Vet) and in VMI 705, Advanced Immunology.

service

outreach focus

A focus of our laboratory is developing and presenting activities for middle and high school students. One activity is Immunity and You –a web and CD-based Immunology Curriculum for high school|http://www.nbtc.cornell.edu/mainstreetscience/immunity_and_you.html.||We also participate in many workshops like EYH and GEMS, aimed at interesting young girls in careers in science.
Keywords: autoimmune disease, bovine and ovine immunology, cellular immunology, diagnostics, environmental toxicology, immunology, livestock vaccines, responses to vaccines